Background
Kalter, Harold was born on February 26, 1924 in New York City. Son of Samuel and Rose Kalter.
(There is still no clear understanding of what causes the ...)
There is still no clear understanding of what causes the great majority of human congenital malformations. And since in most sorts of human disease and pathology that yet prevail prevention usually awaits understanding of cause, it is generally thought that the same is true of developmental aberrations. But is this true? For the relatively few congenital malformations whose causes are primarily environmental, it is plain that their discovery has enabled prevention, but not nec essarily immediately. It took a generation from the time of the discovery that maternal rubella was teratogenic to learn how to immunize against it. Much debate occurred before it was appreciated that thalidomide was a teratogen, and only its removal from the pharmacist's shelf and the end of the epidemic of limb defects attributed to the drug overcame the last doubts. For other proven environmental teratogens doubts and difficulties still con tinue. The claimed prevalence of fetal genital distortions due to female sex hor mones may have been exaggerated. Some potentially teratogenic therapeutic drugs, like anticoagulants, anticonvulsants, and anticancer chemicals, are still pre scribed despite this danger because of their benefits to pregnant women. For those congenital malformations whose basis is predominantly genetic or chromosomal it is different, however. Prevention has not been achieved by the discovery of such causes, as dramatic and revolutionary as some of them have been, except in the questionable sense of interference with reproduction by genetic coun seling or prenatal elimination. But this has not inhibited the romanticists.
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( Serious congenital malformations are a major contributo...)
Serious congenital malformations are a major contributor to the infant death rate worldwide. Their nonhereditary causes are multiple and complex, and include infectious and metabolic dangers, disease medication, nutritional inadequacy, medicinal products, environmental agents and pollutants, among them. The cause of many however is still unknown. The wide range of these causes makes the defects of interest to those of a wide range of medical and investigatory backgrounds, especialy clinicians, fundamental scientists, and environmentalists.
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Kalter, Harold was born on February 26, 1924 in New York City. Son of Samuel and Rose Kalter.
Bachelor, Sir George Williams College, Montreal, 1949. Master of Science, McGill University, Montreal, 1951. Doctor of Philosophy, McGill University, Montreal, 1953.
Postdoctoral fellow United States National Institutes of Health, Montreal, 1953-1955. Research associate Children's Hospital Research Foundation, Cincinnati, 1955-1994. Assistant professor Department Pediatrics, University Cincinnati, 1958-1964.
Associate professor pediatrics University Cincinnati, 1968-1970, professor pediatrics, 1970-1994, professor emeritus pediatrics, since 1994.
(There is still no clear understanding of what causes the ...)
( Serious congenital malformations are a major contributo...)
Sergeant United States Army, 1942-1945.
Married Bella Briansky, November 11, 1945. Children: Eliot Robert, Henry David, John Ferdinand.