He moved to the Soviet Union in 1923, and soon became a film actor. Nersisyan"s first cr was in Namus, a 1925 silent movie. Hrachiya Nersisyan continued acting until the end of his life.
His work included over two dozen films, including several released posthumously.
Hrachia Nersisyan is buried at Komitas Pantheon which is located in the city center of Yerevan.