Background
Arias, Irwin Monroe was born on September 4, 1926 in New York City. Son of Henry Robert and Sylvia (Hirsh) Arias.
(The third edition of this classic work incorporates the p...)
The third edition of this classic work incorporates the past six years' groundbreaking discoveries on the structure and function of the liver and the mechanisms underlying liver diseases. Ten new chapters focus on advances in molecular, cellular, and immunobiology, including such areas as mechanisms of signal transduction, growth control, and cell death; biliary cell and membrane biology; the hepatic microcirculation; transformation in the liver; and molecular aspects of autoimmune liver disease. The section on pathobiologic mechanisms includes new chapters on immune mechanisms of cellular injury in viral hepatitis; viral mechanisms in hepatic oncogenesis; the pathobiology of portal hypertension; and fibrogenesis. Seven new chapters explore major areas of future research, such as liver stem cells; hepatocyte transplantation; gene therapy by targeting nucleic acids to hepatocytes; the process of adoptosis in liver adaptation and carcinogenesis; regulation of the eukaryotic cell cycle, mechanisms of action of the immunosuppressants cyclosporin A and FK-506; and transgenic and "gene-knockout" animal models of liver disease. All chapters from the Second Edition have been updated.
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Arias, Irwin Monroe was born on September 4, 1926 in New York City. Son of Henry Robert and Sylvia (Hirsh) Arias.
Bachelor of Science, Harvard University, 1947; Master of Science, Columbia University, 1948; Doctor of Medicine cum laude, State University, New York Medical Center, 1952; M.D. cum laude, New York Medical Center, 1952.
Intern, Fourth Medical Svc. (Harvard) Boston City Hospital, 1952-1954;
assistant resident, Fourth Medical Svc. (Harvard) Boston City Hospital, 1954-1955;
United States Public Health Service fellow gastroenterology/liver disease, Second and Fourth Medical Svc., 1955-1956;
fellow hematology, Boston Veterans Administration Hospital., 1954-1955;
research fellow, New York Heart Association
senior research fellow, Albert Einstein College Medicine, 1956-1958;
assistant professor, Albert Einstein College Medicine, 1960-1964;
associate professor, Albert Einstein College Medicine, 1964-1969;
assistant visiting physician, Bronx Municipal Hospital Center, 1956-1964;
associate, Bronx Municipal Hospital Center, 1964-1967;
attending physician, Bronx Municipal Hospital Center, 1969-1984;
principal investigator, United States Public Health Service GI training program
director program and chief division gastroenterology-liver disease, Albert Einstein College Medicine, Bronx, 1967-1984;
professor medicine, Albert Einstein College Medicine, 1969-1984;
vice department chairman medicine, Albert Einstein College Medicine, 1973-1984;
director, Liver Research Center, 1973-1984;
associate chairman academic development, department medicine, Liver Research Center, 1980-1984;
professor, department chairman physiology-pathophysiology, Tufts U. School Medicine, Boston, since 1984;
professor medicine, Tufts U. School Medicine, Boston, since 1984.
Consultant Rockefeller Foundation, 1958-1960, Pan American Union, 1959-1963.
(The third edition of this classic work incorporates the p...)
Member overseas medical advisory board Tel Aviv U. School Medicine, 1963-1969. Member of national advisory board La Leche League, since 1970. Trustee Mount Desert Island Biological Laboratory, 1969-1971.
Member of advisory board Children's Medical Research Center, Cincinnati, 1976-1981. Member of national board American Liver Foundation. Member board The Medical Foundation.
Member American Association for the Advancement of Science, American Society Clinical Investigation (vice president), American Association Study LiverDisease (Distinguished Achievement award 1993-1994), American Federation Clinical Research, American Gastroenterol. Association, The Harvey Society, American Physiological Society, International Association Clinical Investigation, International Association Study Liver, Association Am.Physicians, Alpha Omega Alpha.
Married Lyuba Varticouski. Children: Jonathan, Linda, Wendy, Nancy.