Isabel dos Santos is the daughter of President dos Santos and his first wife, Tatiana Kukanova, a Russian chess champion
Isabel dos Santos was born on April 1, 1973, in Azerbaijan, which was then a part of the Soviet Union. She is the oldest daughter of José Eduardo dos Santos, who rose to the presidency of Angola six years after her birth, and his first wife, Tatiana Kukanova, who was a Russian citizen.
José Eduardo dos Santos and Kukanova had met while José Eduardo dos Santos was studying in Azerbaijan. He is the son of parents from São Tomé and Príncipe, and he went to Azerbaijan to study radar communications and petroleum engineering.