Her father, Percy Avery Rockefeller, was one of the richest financiers and industrialists of his time. Percy was a son of Standard Oil co-founder William Avery Rockefeller Junior. and Almira Geraldine Rockefeller. Isabel"s mother, Isabel Goodrich Stillman, was a daughter of banker James Jewett Stillman and Sarah Elizabeth Rumrill.
She attended Westover School and was a member of Junior League, of which she took an active part.
She also performed singing and dancing numbers. She studied bacteriology at Columbia University for three years, and then went to Europe for 5 months with her mother. She was a frequent face in New York high society since her introduction as a debutante in 1920.
In January 1925, a false rumor was spread that she was to marry Alexander Thayer, son of Russell Thayer of Philadelphia.
In June 1925, it was announced that she would marry Frederic Walker Lincoln IV. The day after the wedding, the newlyweds were again honored at a large function at the Field Club of Greenwich. A week-long honeymoon in Buenos Aires followed in November.
Isabel and Frederic had four daughters: Isabel, Calista, Percy, and Florence. She died on March 23, 1980.
She became a member of the advisory board and helped produce a play called Ready Made.
