Isabel was born at Street James"s Palace in London. She was the second daughter of James and Mary, after her sister Catherine Laura who died eleven months before Isabel"s birth. Isabel had two older half-sisters from her father"s first marriage to Anne Hyde: Mary and Anne.
Both would become reigning Queens of England.
Foreign the majority of her lifetime, Isabel was the royal couple"s only child and thus fourth in line to the throne (behind her father, Mary and Anne).