At the age of 13, Zolfonun enrolled the National School for Iranian Music to study musical theory, composition and technique under Ruhollah Khaleghi and Musa Khan Maroufi. While he immediately fell in love with setar, the instrument was not taken seriously in those times. In 1967, Jalal Zolfonun was accepted into the faculty of the fine arts department of Tehran University, where he would further study the setar with Master Noor Ali Boroumand and Dariush Safvat.
From then on, he dedicated himself to the delicate instrument.
He began combining the techniques of the older masters of Setar (an Iranian instrument with four metal strings) with his own ingenuity and mystic sensitivity. Foreign the first time, with Iran"s leading classical singer Shahram Nazeri, he founded an ensemble composed of only Setar players.
Later on in 1980s, Zolfonoun and Nazeri"s compositions were released in two best-seller albums one of which Gol-e Sadbarg (which means, One hundred-petalled Rose), is indisputably the best selling album of classical Iranian music ever. At the same time, Jalal also composed for the Setar in mind and would prove one of the most expressive, while technically virtuosic players of the instrument.
Perhaps most notable of Jalal Zolfonun"s contributions to this music is that he showed for the first time the power and versatility of the setar as an ensemble and solo instrument that could fully express the nuances of Persian traditional music in any setting.
In fact, since Gol-e Sadbarg"s success, the Setar evolved from the least to the most popular instrument in Iran. Following the success of Gol-e Sadbarg, Jalal Zolfonun continued to record a number of other albums on which he is featured as lead soloist, composer and/or ensemble player with a number of well-known singers and musicians with whom he also toured worldwide. Zolfonun also wrote a seminal book on "Setar Playing / Teaching Method".
Zolfonun died of heart disease on 18 March 2012 in Tehran.
He had been hospitalized for two weeks prior to his death for heart failure.