Jerome attended the Massapequa High School and the East Lake Elementary School for his preliminary education. At the age of 16, he volunteered at the Kibbutz Sa'ar, a collective community in Israel.
Seinfeld studied communications and theater at Queen's College, City University of New York, and shortly after graduation in 1976 he made his stand-up debut at an open mic night in Catch a Rising Star nightclub.
Jerry developed an interest in Stand-Up Comedy after brief stints in College Productions. Right after graduation from Queens College, he tried out at an Open Mic Night at New York City's catch a Rising Star in 1976. Soon after, he appeared in a Rodney Dangerfield HBO Special. When he first started doing Stand-Up Comedy, his mother and sister said he would never be as funny as his father.
In May 1981, Seinfeld made a highly successful appearance on "The Tonight Show Starring Johnny Carson." He then became a regular on similar shows, including "Late Night With David Letterman" and "The Mery Griffin Show."
He was ranked #12 in Comedy Central's List of the 100 greatest Stand-Ups of all time.
Jerry created "Seinfeld" with Larry David in 1989 for NBC. By its fourth season it had become the most popular and successful sitcom on American television. The show left the air in 1998 but is still receiving heavy airplay in syndication.
The show also starred «Saturday Night Live» veteran Julia Louis-Dreyfus, as well as experienced actors Michael Richards and Jason Alexander. On the show, Jerry played a caricature of himself and has said that his show was inspired by the 1950s sitcom "The Abbott And Costello Show."
After "Seinfeld" ended, Jerry returned to Stand-Up Comedy instead of pursuing a film career as many other popular comedians have done. In 1998, Seinfeld went on tour and recorded a comedy special entitled "I'm telling you for the last time." The process of developing and performing new material at clubs around the world was chronicled in a 2002 documentary, "Comedian," which focused also on fellow comic Orny Adams. He has written a few books, mostly archives of past routines.
Jerome married to Jessica Sklar on December 25, 1999.