Student, Fordham University, 1949-1950; student, Miami University, Oxford, Ohio, 1950-1951.
Born in Brooklyn, Santos was a football player at Fordham University, and even turned semi-pro, before finding a new avenue in acting. He had brief parts in several lesser-known films, and made a number of guest appearances on television shows throughout his acting career, frequently in the stock character role of a police officer He also appeared on The Sopranos as Angelo Garepe in seven 2004 episodes.
From 1978-1980 Santos appeared on the Columbia Broadcasting System game show The Match Game always sitting in the top left seat.
He appeared in numerous episodes and was usually comic foil to Brett Somers. He died four days later at the age of 84.
Served with Medical Corps Army of the United States, 1952-1954.
Married Mary Montero, March 31, 1958. Children: Joseph, Perry.