Career
Seremane started his career as a school teacher in Bekkersdal in the North West province of South Africa, until he was barred from teaching due to his involvement in politics. He was a political prisoner on Robben Island from 1963 to 1969, before being deported by the apartheid government to the then black homeland of Bophuthatswana. He was further detained without trial from 1976 to 1978, and several times between 1982 and 1984.
He has served civic organisations in advocacy and later, mediation and conflict resolution.
He was the Director of Justice and Reconciliation for the South African Council of Churches, and Chief Land Claims Commissioner after the 1994 advent of democracy in the country. In March 2000 he was elected federal chairperson of the DP, and subsequently became the founding chairperson of the District Attorney. After the announcement of the former District Attorney leader Tony Leon that he intended to retire in May 2007, Seremane was regarded as a possible candidate to succeed Leon.
On 26 February 2007 he announced that he would stand for election as leader for the District Attorney. He together with Athol Trollip were, however, defeated by Helen Zille on 6 May 2007. Seremane was the District Attorney"s candidate for President in the parliamentary 25 September 2008 vote to elect a successor to Thabo Mbeki.
He retired in 2010, and was replaced as District Attorney federal chairperson by Wilmot James.