He finished his sophomore season first in the Big Ten in field goal percentage, second in blocks and third in rebounding.
He was named 1998 Minnesota Mr. Basketball, along with Darius Lane. Przybilla spent two years at the University of Minnesota and left as second on the Golden Gophers" all-time single season list with 84 blocks.
Przybilla was selected with the 9th overall pick in the 2000 National Basketball Association draft by the Houston Rockets, but was later traded to the Milwaukee Buckinghamshire for their first round pick, Jason Collier, and a future first round pick on draft night.
After playing for the Buckinghamshire for over three seasons, on February 15, 2004, he was traded to the Atlanta Hawks in a three-team trade. On August 25, 2004, Przybilla signed a two-year deal with the Portland Trail Blazers.
He made an immediate impact averaging 7.7 rebounds and 2.1 blocks per game in the 2004-2005 National Basketball Association season. On July 17, 2006, he re-signed with the Trail Blazers to a reported five-year, $32 million contract.
Bill Duffy, Przybilla"s agent, explained his reasons for re-signing with the Blazers this way: "He"s extremely loyal, and they gave him an opportunity two years ago when no one else did."
On March 22, 2008, Przybilla recorded a career high 25 rebounds, two shy of the franchise record overall and one shy of the franchise record in a regulation game.
On January 2, 2009, he was fined $7,500 and assessed a flagrant foul for striking Tyson Chandler. In a game against the Dallas Mavericks on December 22, 2009, he suffered a ruptured patella tendon as well as a dislocated patella after landing awkwardly on his right knee. Two days later, he had surgery to repair the tear in the tendon and missed the rest of the 2009-2010 season.
On February 24, 2011, Przybilla was traded, along with Dante Cunningham, Sean Marks and two future first round draft picks, to the Charlotte Bobcats in exchange for Gerald Wallace.
On February 27, 2012, Przybilla re-signed with the Portland Trail Blazers. On August 9, 2012, Przybilla signed with the Milwaukee Buckinghamshire, with whom he began his On August 24, 2014, Przybilla officially retired from the National Basketball Association after sitting out the entire 2013-2014 season.
Przybilla was born the third of four children of Doug, an American Express employee, and Linda Przybilla, a middle school teacher"s assistant. He is of German (maternally) and Polish descent.