Associate of Arts in Chemistry, Santa Ana College, 1957. Bachelor of Science in Chemistry, University Redlands, 1960. Doctor of Medicine, University of California at Los Angeles, 1965.
Medical intern, assistant resident in medicine Johns Hopkins Hospital, Maryland, 1965-1967. Fellow in medicine Johns Hopkins University, Baltimore, 1965-1967. Research associate laboratory physiology National Cancer Institute National Institutes of Health, Bethesda, Maryland, 1967-1969.
Clinical and research fellow endocrine unit Massachusetts General Hospital, Boston, 1969-1972, investigator Howard Hughes Medical Institute, since 1976, chief laboratory molecular endocrinology, since 1979, director endocrine division, since 1991. Visiting scientist department biology Massachusetts Institute of Technology, Cambridge, 1970-1980. Associate professor medicine Harvard Medical School, Boston, 1975-1988, professor medicine, since 1989.
Member American Society Clinical Investigation, American Society Biological Chemists, Association American Physicians, Society Experimental Biology and Medicine, Endocrine Society (Edwin A. Astwood lecturer award 1979, Robert H. Williams Distinguished Leadership award 1999), Alpha Omega Alpha.