He worked for the church in New England, Michigan, Ohio, Great Britain, and California. He then published another book, "The Great Second Advent Movement", in 1905. In it Loughborough describes his first-hand experiences in the history of the church, the visions and prophecies of Ellen White, early divisions in the church, and various philosophical and religious matters, as well as some autobiographical material.
F. C. Gilbert (1867-1946) discusses Loughborough"s experiences with Ellen White"s visions in his book "Divine Predictions of Mistress
Ellen G. White Fulfilled", especially her predictions involving slavery and the onset of the American Civil War. The John Loughborough School(1980-2013) in Tottenham, North London, was named after him.
One well known quote by Loughborough appeared in an October 8, 1861 Review and Herald article (now the Adventist Review), in which he was quoted speaking against the formation of creeds:
"The first step of apostasy is to get up a creed, telling us what we shall believe. The second is, to make that creed a test of fellowship.
The third is to try members by that creed.
The fourth to denounce as heretics those who do not believe that creed. And fifth, to commence persecution against such.".