John Poyntz was an English courtier and politician, Member of Parliament for Devizes in 1529.
Poyntz was the second son of Sir Robert Poyntz of Iron Acton, Gloucestershire, by Margaret, an illegitimate daughter of Anthony Woodville, 2nd Earl Rivers, making Margaret a first cousin of King Henry VIII.
Poyntz married, by 1528, Elizabeth, the daughter of Sir Matthew Browne of Betchworth Castle, Surrey. Poyntz was sewer to Queen Catherine of Aragon in 1520. A painting and a drawing of Poyntz by Holbein survive.