Sometime between 1776 and 1780 he became an apprentice to John Howe, in Newport, Rhode Island. John Ryan married Amelia Mott on 22 November 1781 in New York City. His relationship with William Lewis dissolved and the publication underwent a name change in 1786 to the Saint John Gazette, and Weekly Advertiser with John Ryan as the publisher.
1799 - Acquired the Royal Gazette from Christopher Sower and sold Saint John Gazette to Jacob South. Mott.
1807-1830"s - Publisher of Newfoundland"s first newspaper Royal Gazette and Newfoundland Advertiser, in Saint John"s, Newfoundland. John Ryan and Amelia Mott had seven children:
Michael Ryan - printer of the Globe in Barbados.
Lewis Kelly Ryan - publisher of Newfoundland Sentinel, and General Commercial Register
Robert B. Ryan
Mary Somerindyke Ryan