Karl Sebastian Roth

Background

Roth, Karl Sebastian was born on March 3, 1941 in New York City. Son of Victor and Ruth Leila (Fisher) Roth.

Education

Bachelor, U. Rochester, New York, 1963; Doctor of Medicine, Wake Forest U., 1969.

Career

Pediatric intern, Medical College Pennsylvania, Philadelphia, 1969-1970; pediatric resident, Thomas Jefferson U., Philadelphia, 1970-1972; fellow genetics/metabolism, University of Pennsylvania, Philadelphia, 1972-1975; assistant professor pediatrics, University of Pennsylvania, Philadelphia, 1975-1982; professor pediatrics, biochemistry and molecular biophysics, Medical College Virginia, Richmond, since 1982. Consultant state newborn screening program Commonwealth Virginia, Richmond, since 1982. Member governor's genetics advisory board Commonwealth Virginia, Richmond, since 1982.

Member board Clinical Pediatrics, Cleveland, since 1988. Visiting professor pediatrics U. Zurich, Switzerland, 1993.

Achievements

• Achievements include development of prenatal therapy of an inborn error of metabolism for the second disease in medical history (Holocarboxylase Synthase Deficiency). Establishment and characterization of (biochemically and physiologically) the first animal model for the human renal fanconi syndrome based upon use of a physiologically producedcompound. Discovered and characterized a unique inborn error of metabolism.

Membership

Board member Agoraphobics Building Indiana Lives, Richmond, since 1987, Governor's Coun.on Child Mental Health, Richmond, since 1989. Participant Children's Miracle Network Telethon, Richmond, since 1989. Member American Pediatric Society, Society Pediatric Research, Federation American Socs.

Exptl.Biology, Society Inherited Metabolic Disorders, Sigma Xi.

Connections

Married Beverly Rochelle, April 16, 1967 (divorced July 1984). Children: Christopher Geordie, Marcus Amadeus. Married Lydia Carole Noland, July 28, 1984.

1 child, Alexander Kristof Parham.

Father:

Victor Roth

Mother:

Ruth Leila (Fisher) Roth

Spouse:

Lydia Carole Noland

Spouse:

Beverly Rochelle

child:

Marcus Amadeus Roth

child:

Alexander Kristof Parham Roth

child:

Christopher Geordie Roth