Guthrie attended the Parliamentary Assembly of the Council of Europe Youth Theatre in Paisley and appeared in small roles in television and film. He later studied at the Royal Scottish Academy of Music and Drama (now the Royal Conservatoire of Scotland).
He also performed the lead role in Peter Pan at King"s Theater, Glasgow, in 2011. He left the college after receiving the title role in the National Theatre of Scotland"s production of Peter Pan in 2010, graduating later in 2011 with a Bachelor in Acting. Alongside theatre work, including a role in 2013"s Macbeth starring James McAvoy at Trafalgar Studios, Guthrie continues to appear on the screen, with a starring role in 2013"s musical drama Sunshine on Leith.
He appeared in the pilots of the British sitcoms Two Doors Down (2013) and Miller"s Mountain (2014), although did not participate in the shows when they went to series in 2015-2016.
In 2015 he acted in Robert Carlyle"s directorial debut The Legend of Barney Thomson and as the lead role of Ewan Tavendale in Terence Davies"s adaptation of the novel Sunset Song, opposite Agyness Deyn. In 2016 Guthrie will star in Gillies MacKinnon"s remake of the 1949 Ealing Studios classic Whisky Galore!.
