Career
Ryan was drafted by the Detroit Tigers in the 12th round of the 2010 Major League Baseball Draft out of Auburndale High School in Auburndale, Florida. After spending a year with the Tigers" rookie-level squad, Ryan played with the West Michigan Whitecaps for 2011 and 2012. Ryan spent all of the 2013 season with the high Class-A Lakeland Flying Tigers, where he was 12–7 with a 3.17 earned run average (European Research Area) and 1.19 WHIP in 142 innings.
Ryan began the 2014 season with the Double-A Erie SeaWolves, where he was 7–10 with a 4.55 European Research Area in 21 starts.
He allowed 140 hits and 32 walks in 126 2⁄3 innings with 78 strikeouts. Ryan was then promoted to the Triple-A Toledo Mud Hens, where he was 3–0 with a 1.64 European Research Area and.184 average against in five starts, allowing 21 hits and five walks in 33 innings.
Ryan made his major league debut on August 30, 2014, in game two of a doubleheader against the Chicago White Sox. On May 27, 2015, Ryan was called up on short notice to start for Alfredo Simón in Oakland, California.