They had two daughters: Anna Maria (Rome, 1637 - Paris, February 4, 1672) and Laura (Fano, May 27, 1639 - Rome, July 19, 1687). Queen Anne personally took care of the girls" education. Her brother managed to find good matches for the Martinozzis: Laura was married to Alfonso IV d"Este.
Anna Maria to Armand, Prince of Conti.
A daughter of Laura, Maria Beatrice d"Este, became Queen of England, Scotland and Ireland through marriage to James II of England.