1915
Leo Loeb
Rämistrasse 71, 8006 Zürich, Switzerland
Loeb's disapproval of rising German nationalism and militarism led him to take up medicine at the University of Zurich in 1890-1892. He did his clinical work at the University of Edinburgh and the medical school of London Hospital, occasionally attended lectures at other London medical schools, and returned to Zurich to complete his medical studies in 1895-1897. In his work toward the Doctor of Medicine degree, which required a thesis, he did skin transplantation experiments on guinea pigs under the direction of the pathologist Hugo Ribbert.
Rämistrasse 71, 8006 Zürich, Switzerland
Loeb's disapproval of rising German nationalism and militarism led him to take up medicine at the University of Zurich in 1890-1892. He did his clinical work at the University of Edinburgh and the medical school of London Hospital, occasionally attended lectures at other London medical schools, and returned to Zurich to complete his medical studies in 1895-1897. In his work toward the Doctor of Medicine degree, which required a thesis, he did skin transplantation experiments on guinea pigs under the direction of the pathologist Hugo Ribbert.
https://www.amazon.com/Heloderma-Collaboration-Elizabeth-Corson-White-Fleisher/dp/B079FLYHWP/ref=sr_1_5?dchild=1&keywords=Leo+Loeb&qid=1591171858&sr=8-5
1913
https://www.amazon.com/Biological-Basis-Individuality-L-Loeb/dp/B001JYQ2EY/ref=sr_1_2?dchild=1&keywords=Leo+Loeb&qid=1591171858&sr=8-2
1945
educator pathologist physician scientist
Loeb was born on September 21, 1869, in Mayen, Prussia (now Germany). His mother, Barbara Isay Loeb, died when he was three; his father, Benedict Loeb, died of tuberculosis when the boy was six. He lived with his maternal grandfather in Trier and at age ten moved to Berlin to live with a maternal aunt and uncle, whose daughter Helene married Albert Schweitzer.
Tuberculosis and other ailments interrupted Loeb’s schooling and recurred occasionally during his life. After 1889 he attended for short periods the universities of Heidelberg, Berlin, Freiburg (where he studied with August Weismann) and Basel (where he studied with Bunge and Miescher). His disapproval of rising German nationalism and militarism led him to take up medicine at the University of Zurich in 1890-1892. He did his clinical work at the University of Edinburgh and the medical school of London Hospital, occasionally attended lectures at other London medical schools, and returned to Zurich to complete his medical studies in 1895-1897. In his work toward the Doctor of Medicine degree, which required a thesis, he did skin transplantation experiments on guinea pigs under the direction of the pathologist Hugo Ribbert.
In 1897, Loeb went to Chicago, where his older brother Jacques was a physiologist at the University. He had previously visited his brother at Woods Hole, Massachusetts, in 1892 and 1894. During five years in Chicago, Loeb practiced briefly near the University of Chicago, where he was physician to John Dewey’s experimental school and was adjunct professor of pathology at Rush Medical College (later affiliated with the University of Illinois). In a rented room behind a drugstore he did experimental research on the healing of skin wounds of guinea pigs; he extended this research during a brief stay at Johns Hopkins School of Medicine, where he met William Osier, W. S. Thayer, and L. F. Barker (internal medicine); W. S. Halsted (surgery); W. H. Welch and Simon Flexner (pathology); and Mall and Harrison (anatomy). He also did research during summers at the Marine Biological Laboratory at Woods Hole.
Loeb next held a research fellowship under Adami at McGill University in 1902-1903. He was assistant professor of experimental pathology at the University of Pennsylvania in 1904-1910; directed laboratory research at Barnard Skin and Cancer Hospital, St. Louis, 1910-1915; and was professor of comparative pathology at Washington University, St. Louis, in 1915-1924, succeeding Eugene L. Opie as Mallinckrodt professor of pathology and department chairman in 1924-1937. He became emeritus professor of pathology in 1937 but continued to work as research professor (endowed by the Oscar Johnson Institute) until his final retirement in 1941 at the age of seventy-two.
Loeb continued to do research during summers at the Marine Biological Laboratory until 1950, when he nearly died of tuberculosis. Remaining thereafter in St. Louis, he worked on two books, one on the causes and nature of cancer and the other on the psychical factors of human life; both were unfinished at his death.
Among Loeb’s honors were appointments to two endowed professorships; the John Phillips Memorial Prize (1935), awarded annually to an outstanding physician by the American College of Physicians; an annual lectureship in his name, endowed by his students at Washington University; an honorary D.Sc. from Washington University in 1948; and election as a member and officeholder in national and international medical and scientific organizations.
Loeb can be placed among the pioneers in studying the compatibility reactions of hosts toward transplanted tissues of the same and different species. His chief research writings were on tissue and tumor growth, tissue culture, pathology of circulation, venom of Heloderma, analysis of experimental amoebocyte tissue, internal secretions, and the biological basis of individuality.
Over several years, Loeb showed clearly that the growth of certain epithelial malignancies in animals could be modulated by removal of the ovaries. That work predated clinical application of the same concept in human breast cancer by several decades. He later worked on tissue transplantation and cell culture, as well as endocrine disease.
Fellow
American Association for the Advancement of Science , United States
President
American Association Pathologists and Bacteriologists , United States
1914 - 1915
American Physiological Society , United States
President
Society of Cancer Research , United States
1911 - 1912
Society of Experimental Medicine and Biology , United States
Society Experimental Medicine and Biology , United States
Association American Physicians , United States
American Philosophical Society , United States
American Medical Association , United States
Vice-President
International Association for Cancer Research
Loeb was known as a patient, kind, and helpful mentor to younger colleagues in the department.
On January 3, 1922, at the age of fifty-three, Loeb married Georgianna Sands, a physician in Port Chester, New York. She became not only his spouse, but also his scientific, administrative, and literary partner for the remainder of their lives together.
