Her most famous cartoon is Nemi. After a short study of graphical design at the Santa Monica College of Art in California, Lise Myhre started her career as an artist, earning money illustrating Civil Defense covers and t-shirts. She also participated in cartoon competitions and started giving contributions to Larsons Galne Verden, the Norwegian version of Gary Larson"s magazine The Far Side ("Member of Parliament" in 1996).
From 1997, Myhre was given her own page in Larsons Gale Verden, "Den svarte siden" (English: the Black Side/Page), and this developed into Nemi.
From 1999, Nemi was a guest cartoon in the Norwegian newspaper Dagbladet, and from 2000 as a regular. The first Nemi album was published the summer 2000, and it was a great success.
Since Myhre changed publisher, from Bladkompaniet to Egmont, in January 2003, there is a new Nemi magazine published every 6 weeks. Nemi, with a circulation of more than 70,000 copies, is now one of the two most popular cartoons in Norway, next to Pondus.
Nemi is today published in approximately 60 different newspapers, magazines and websites in Norway, Sweden, Denmark, Finland.
Amongst these, Dagens Nyheter (Sweden), Ilta-Sanomat (Finland) and Dagbladet (Norway) are the biggest. Lise Myhre has also illustrated poems by Edgar Allan Poe and André Bjerke.