Career
However, with the decline of Mongol rule the Yuan court had less resources to monitor Tibetan affairs During the era of Lotro Gyaltsen the holders of the office were Wangtson (1347-c 1350), Gyalwa Zangpo (c 1350-1356/58), Namkha Tenpai Gyaltsen (c 1357 and c 1364) and Palbum (?-1360). Meanwhile Phagmodru, one of the 13 myriarchies (trikor) of Central Tibet, had become an increasingly assertive force under its energetic leader Changchub Gyaltsen.
Changchub Gyaltsen was imprisoned by the dpon-chen Gyalwa Zangpo in 1346, but was released in the next year since Gyalwa Zangpo felt discontented with being replaced by Wangtson and wanted a strong ally.
During the next years Changchub Gyaltsen fought Wangtson and various local regimes in Central Tibet with relative success. In about 1350 Changchub Gyaltsen had become the dominating power in Ü (East Central Tibet).
This was followed by the sudden demise of the dpon-chen Gyalwa Zangpo, possibly through foul play. Other information implies that Lotro Gyaltsen remained abbot until his death in 1365.
Whatever the case, Changchub Gyaltsen ruthlessly crushed the last resistance by the ex-dpon-chen Wangtson in 1358 and was established as regent of entire Central Tibet (Ü-Tsang).