Doña Luisa was the only daughter of Don Pedro Pérez de Tagle, brother of the Marquis of Sierra Nevada and Doña Manuela Sánchez de Tagle, who is by her own right the 3rd Marquesa of Altamira. She was born on May 15, 1715 in Vera Cruz, Mexico, and had was baptized on May 23, 1715.
Her husband received from her the hacienda of Cuisillos as dowry and he himself became the Marquis Consort of Altamira. Together, the couple had three children:
Juana Rodríguez de Albuerne y Pérez de Tagle
She was the third cousin of Ana Manuela Muñíz y Sánchez de Tagle, wife of the powerful nobleman Isidro Huarte y Arrivillaga, parents of Empress Ana Maria of Mexico.
Manuel Rodriguez de Albuerne y Pérez de Tagle who married María de la Paz Girón Moctezuma, a direct descendant of Emperor Moctezuma II, and a member of the family of the Duke of Moctezuma de Tultengo
Cecilia Rodríguez de Albuerne y Pérez de Tagle who married Domingo Trespalacios Escandón, a judge in the Audiencia of Mexico and a member of the Council of Indies.
