His work appears internationally in economic, intellectual, political and cultural magazines. He is particularly known for his work for reformist papers in Iran and Persian language websites Radio Zamaneh, Tavaana: East-Learning Institute for Iranian Civil Society, and IranWire. He is also well-known because of his cartoons about Iranian presidential election, 2009.
He lives in France.
Touka Neyestani a fellow cartoonist as well is Mana"s older brother. Mana has a master"s degree in Architecture from the University of Tehran. Mana began his professional cartooning career in 1989, and started drawing editorial cartoons in 1998, for Zan.
During 1998-2000, he drew a large number of cartoons for various reformist newspapers, such as Asr-e Azadegan, Sobhe Emrooz, Mosharekat, Azad, Neshat (as a freelancer), and Aftab-e Emrooz (as a staff cartoonist).
His cartoons are published regularly on the website of Iranian exile media Radio Zamaneh, as well as Tavaana: East-Learning Institute for Iranian Civil Society and IranWire. Riots erupted by ethnic Azerbaijanis in Iran when they took offense to a Neyestani cartoon published in the children"s section of the 12 May 2006 supplement of Iran, a government-run newspaper.
The cartoon depicted a cockroach responding in Azerbaijani. Neyestani, along with Mehrdad Ghasemfar, the editor-in-chief of Iran, were arrested by government officials and the newspaper was closed down following the riots.
He finally ended up in exile in France where he published a graphic novel titled "An Iranian Metamorphosis," about his time in prison.