Background
He was the son of Constantine Kamytzes and Maria Angelina, who was the granddaughter of the Byzantine emperor Alexios I Komnenos and Irene Doukaina through her mother Theodora.
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Manuel Kamytzes
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Career
He was therefore a first cousin of the emperors Isaac II Angelos and Alexios III Angelos, and of Michael I Komnenos Doukas, who was to be despot of Epirus. He led Imperial troops in 1189, when the Third Crusade crossed Byzantine territory. Manuel afterwards fought against a rival Bulgarian leader, Ivanko, and was captured.
The emperor took no steps to ransom him.
Manuel"s wife"s name is unknown. He also had a son, named John Kamytzes (Ioannes Kamytzes).
