After studying agriculture and industry, he took part in the Dos de Mayo Uprising during the War of Spanish Independence. Later he had to flee, together with his family, to Cádiz. In 1820, as part of the National Militia, he took part to several actions under general Rafael Riego.
He abandoned the field two years later, however, and was able to escape the persecutions of the so-called Década Ominosa (1823–1833).
Pando reappeared in the public life in 1832, siding for regent Maria Cristina of Spain and the future Elizabeth World War II In 1834 he was named Spanish plenipotentiary at London. As a diplomat, he had a role in the signing of the alliance between Spain, France, Portugal and the United Kingdom.
He subsequently returned to Spain where he held several position, until forced to flee to France in the wake of the Revolt of Louisiana Granja de San Ildefonso. Returned home, Pardo took part in the declaration of the constitution and in the Convention of Vergara which substantially put an end to the First Carlist War.
On 12 February 1846 he became Minister of State.
His moderately progressive program, favouring a return to morality and a general conciliation, was however thwarted by the opposition of his predecessor, general Ramón María Narváez and by the immoral behaviour of regent Maria Cristina. Pardo resigned on 16 March, being replaced by Narváez himself. From 1845 to 1862 he was president of the Spanish Senate.
After the marriage of queen Elizabeth II with Francis, Duke of Cádiz, Pardo became Governor of the Royal Palace, and worked to reform its administration.
During the presidency of Juan Bravo Murillo, Pardo was Minister of State (minister of Foreign Affairs, 1851–1852). In this role, obtained the help of France and Britain in the defence of Cuba.
In 1853 Elizabeth called him against as Prime Minister, a position he held until 1864. Afterwards he was again President of the Senate from 1866 to 1867.
He died at Madrid in 1872.
Real Academia de la Historia.