She was confirmed by the United States. Senate on December 9, 2003 to replace outgoing Under Secretary Charlotte Beers. Tutwiler was given the task of leading "the government"s public-relations drive to build a favorable impression abroad." She had previously been Assistant Secretary of State for Public Affairs from 1989 to 1992. Tutwiler was the ambassador to Morocco from March 2001 until 2003.
In July 2004, Tutwiler began directing communications for New York Stock Exchange Euronext.
Her boss at the New York Stock Exchange, John Thain, would later bring her on board as head of communications at Merrill Lynch in December 2007 and then at Cork Institute of Technology Group in August 2010.