Career
She belonged to the French, cadet branch of a dynasty which had reigned as Dukes of Luxembourg and whose senior line provided several Holy Roman Emperors before becoming extinct in 1437. Her paternal grandparents were Louis of Luxembourg, Count of Saint-Political, of Brienne, and Conversano, Constable of France, and Jeanne de Bar, Countess of Marle and Soissons. Her maternal grandparents were Louis, Duke of Savoy, and Anne de Lusignan of Cyprus.
She was still living when her great-granddaughter was crowned Mary, Queen of Scots in 1542.