Career
He was drafted by the Rams in the seventh round of the 2006 NFL Draft. He played college football at Minnesota. Setterstrom earned All-State, All-Metro, and All-Conference honors as senior at Northfield High School (Minn) where he was a two-way lineman who totaled 127 tackles, six sacks, five forced fumbles, and six fumble recoveries over career for Northfield Raiders.
Also, he was a four-year letterwinner as heavyweight wrestler, compiling a 38-3 record as a senior.
Setterstrom played collegiately at the University of Minnesota from 2002-2005. During his career with the Gophers, Mark was a two-time First-team All-Big Ten selection (2004–2005), a Second-team All-American (2005) and an All-American selection by Rivals.com in 2004.
He was a Second-team All-America and First-team All-Big Ten honors as a senior as a key cog on Gophers’ line that allowed three sacks, lowest in Big Ten and best in school history. He was an Honorable mention All-Big Ten selection in sophomore year. and a Fourth-team All-America Freshman selection by The Sporting News and Big Ten All-Freshman Team.
Pre-draft
(* represents NFL Combine)
Saint Louis Rams
He was drafted by the Rams in the seventh round of the 2006 NFL Draft.
He signed a three-year $1.08 million contract with the Rams on July 22, 2006. In his rookie season with Saint Louis, Setterstrom appeared in seven games, starting six of those at left guard. In 2007 he opened the season as starter at left guard, starting the first three games of the season before suffering a season-ending knee injury in Week 3 and he was placed on reserve/injured list 9/26/2007.
Also he missed all of the 2008 season with knee injuries but was re-signed by the Rams to one-year deal during the 2009 off-season.
Setterstrom was not tendered a contract by the Rams following the 2010 season, making him a free agent.