She graduated from Mount Saint Mary"s University in Emmitsburg, Maryland, in 1984 and the Catholic University of America"s Columbus School of Law in Washington, District of Columbia in 1999.
In October, 2011, Kane became the President and Chief Executive Officer of Sister Cities International. Membership consists of 550 United States cities, counties and states that have over 2000 partnerships in over 140 countries on 6 continents. and Mount Saint Mary"s University. In 1999.
Kane ran unsuccessfully as Republican candidate for the Maryland House of Delegates in District 15 in 2002.
She also ran unsuccessfully for the Montgomery County Council in 2000.
She served as Secretary of State of Maryland from August 2, 2005 to January 17, 2007, and as Member, Governor"s Executive Council, Chair, Governor"s Subcabinet for International Affairs and (2005–2007). Before that, she was Deputy Secretary of State and Chief Legal Counsel, (2003–2005).
Kane was admitted to Maryland Bar in 2001. She served as an Of Counsel with the Ethridge, Quinn, McAuliffe, Rowan & Hartinger law firm in 2001-2002.
Since 2007, Kane worked at the United States Chamber of Commerce as Director of Special Projects, but took a leave of absence to run for Lieutenant Governor.
From 1997 to 2003, Kane was on the Board of Directors of Kane Company, an office moving company that held contracts with various federal agencies. Mary is the daughter of Irish immigrants.
Kane also sits on the board of Suburban Hospital, a member of Johns Hopkins Medicine. She has also been a member of the Governor"s Commission on Maryland Military Monuments 2005-2007), the Governor"s Interagency Council for the Nonprofit Sector, 2005-2006, and served on the Board of State Canvassers, 2005-2007 and Advisory Committee for the Jefferson Patterson Historical Park and Museum, 2005-2007.
Married John Murray Kane, April 12, 1986, 3 children.