Education
Scott did his undergraduate and graduate work at Massachusetts Institute of Technology, with Professor Mary Lou Pardue as his Doctor of Philosophy thesis advisor.
Scott did his undergraduate and graduate work at Massachusetts Institute of Technology, with Professor Mary Lou Pardue as his Doctor of Philosophy thesis advisor.
His tenure began September 1, 2014. Scott was Professor of Developmental Biology, Genetics, Bioengineering, and Biology at the Stanford University School of Medicine prior to his Carnegie appointment. He moved to Indiana University for his postdoctoral work as a Helen Hay Whitney fellow with professors
Thomas Kaufman and Barry Polisky.
After setting up his own lab at the University of Colorado, Boulder, Doctor Scott went to Stanford in 1990 to join the newly formed Department of Developmental Biology, and the Department of Genetics. His research focused on genes that control development, and how damage to these genes leads to birth defects, cancer, and neurodegeneration.
He discovered the “homeobox,” an evolutionarily conserved component of many genes that control development. His lab group discovered the genetic basis of the most common human cancer, basal cell carcinoma, and of the most common childhood malignant brain tumor, medulloblastoma.
Scott served as Associate Chair and Chair of the Department of Developmental Biology for a total of six years.
He chaired the multidisciplinary Biology-X program at Stanford from 2001-2007 and was Company-chair of the Center for Children’s Brain Tumors. His awards include the Passano Award (1990), the Conklin Medal of the Society for Developmental Biology (2004), and the Pasarow Award in Cancer Research (2013). While at Stanford University Doctor Scott studied how embryonic and later development is governed by proteins that control gene activity and cell signaling processes.
He independently discovered homeobox genes in Drosophila melanogaster working with Amy J. Weiner at Indiana University.
Among his laboratory"s many subsequent discoveries, he is recognized for the cloning of the patched gene family and demonstration that a human homolog PTCH1 is a key tumor suppressor gene for the Hedgehog signaling pathway as well as the causative gene for the nevoid basal cell carcinoma syndrome, or Gorlin syndrome. Scott served on the faculty of the Department of Molecular, Cellular, and Developmental Biology at the University of Colorado starting in 1983.
He moved to Stanford University in 1990 to join the faculty of the Department of Developmental Biology and the Department of Genetics. From 2002-2007 he was Chair of Biology-X, Stanford"s interdisciplinary biosciences program
National Academy of Sciences]
He is a member of the American Academy of Arts and Sciences, the National Academy of Sciences, and the Institute of Medicine, and he served as president of the Society for Developmental Biology.
