His first performance in theatre was in 1909 with role of "Bob" in Sherlock Holmes by Arthur Conan Doyle. He ran the Darülbedayi Theatre in Istanbul from its opening in 1914. The marriage lasted until Neyyire"s death in 1943.
Ertuğrul then married Handan Uran (born 1927) in 1950.
A stage actress, she starred in her only movie, the 1953 Halıcı Kız, once again directed by Ertuğrul himself. She survived her husband"s death in 1979.
During his stay in Izmir following the honorary doctor ceremony, Ertuğrul died of a heart attack at the age of 87 on 29 April 1979. He was buried in Zincirlikuyu Cemetery in Istanbul.
Two theatres in Turkey are named in his honor: the Harbiye Muhsin Ertuğrul Stage in Istanbul and the Muhsin Ertuğrul Stage in Ankara.