She is wheelchair-bound due to a car accident at the age of 21. She is also a singer, activist, and a motivational speaker. Muniba Mazari is of Baloch background.
In 2007, Muniba met with an accident when she was en route to her hometown, Rahim Yar Khan, her car fell into the ditch that accident made her paraplegic for the entire life.
As an artist, her first art teacher was her father. She has received Bachelor"s degree in Fine art
She has also established her brand, known as Muniba’s Canvas with the slogan Let Your Walls Wear Colors. Her medium is Oil Pastels.
Muniba Mazari Baloch participated as a motivational speaker at various conferences and forums.
She is also a fellow Piscean, and works as an anchor at PTV, the first wheelchair-bound anchor, and also the first wheelchair-bound model for the prestigious Toni&Guy in Pakistan and the brand ambassador for The Body Shop in Pakistan, and one of the Ponds Miracle Women. also working as brand ambassador for "chughtai lab".