Both of Nancy Pelosi's parents were of Italian descent. Her father was a second-generation immigrant from South Italy, while her mother was a first-generation immigrant from Campobasso, South Italy.
Nancy Pelosi was born on March 26, 1940, in Baltimore, Maryland, the United States, to Thomas Ludwig John D'Alesandro Jr. and Annunciata M. "Nancy" D'Alesandro (née Lombardi). Pelosi carries on the family tradition of being involved in politics. Pelosi's father, Tommy D'Alesandro, was a legendary Democratic congressman and Baltimore mayor. Her brother Thomas would also go on to become mayor of Baltimore. A student of law, she dropped out of law school to get married. She later became a leader at the local Democratic Women's Club.
Nancy was the last of six children and the first daughter. The family lived on Albemarle Street in Little Italy. Their neighborhood was a loyal Democratic Party stronghold in Maryland politics. Little Italy was a working-class and largely Roman Catholic neighborhood, located near the city's main harbor. The local church, St. Leo's, and the nearby Democratic Party office were the centers of social and economic life for Italian-American families.