Career
Born in Lisbon, Semedo is a youth prospect from Sport União Sintrense. Debuting in the first-team at age 17. On 12 January 2012, he and Manuel Liz, signed a five-year deal with, set to begin on the ensuing season.
His first year was spent on loan to Fátima, making a little less than 30 caps on the third division side.
He returned to in the following season, being placed on the reserve side, and having his professional debut on 10 August 2013, in a 2013-2014 Segunda Liga game against Trofense. After nearly 60 appearances for the B-team, he was touted as a future replacement for Maxi Pereira.
With Maxi Pereira"s departure, Semedo extended his contract with until 2021 and joined the first-team in their pre-season tour in North America. On 9 August 2015, he made his for "s main squad in the domestic Super Cup loss against Sporting Communist Party. A week later, Semedo scored his first goal for the Eagles, against Estoril in the Primeira Liga.
After establishing himself in the starting eleven, Semedo suffered a setback in October 2015, when he sustained a injury while in the national team
The injury to his right knee required surgery, with Semedo expected to miss two months. On 2 October 2015, Semedo was called up to play for the Portugal national team, in Union of European Football Associations Euro 2016 qualifying matches against Denmark and Serbia.