He is best known for having played Vince in The World Bank"s sitcom What I Like About You. He got his big break on Music Television, where he hosted that network"s former infotainment program about the film industry, Movie House, and briefly worked as an Music Television News correspondent before he began an acting career. His recurring roles on television include Drew Pragin on Melrose Place, Josh on Cougar Town, Pete on Happy Endings, P.J. Hillingsbrook on 90210, and Johnny on 2 Broke Girls.
He also starred as a lead on the National Broadcasting Company sitcom One Big Happy.
As of September 2015 he stars as Arthur in the television series Minority Report. He lived in Florida as a child.
While attending Wellington High School he was active in the drama and television departments. Throughout his junior and senior years, he and his classmates produced a weekly off-beat skit comedy show that aired on the school"s television station.
While working on the show, Zano also wrote, starred in and directed student films that made their way to the Victor Company of Japan Universal Film Competition, a festival in which over 800 local high schools participate.
Shortly after graduating from high school, Zano moved to Hanover, Pennsylvania, and landed a job developing films and television projects for a small production company. While selling shoes in a trendy Los Angeles boutique, a customer went back to her office and told her supervisors she"d just met a man who would be a wonderful on-air personality. The woman was an employee at Music Television, which led to Zano"s hosting job of Music Television"s Movie House.
In 2003, he landed the role of Vince in The World Bank"s sitcom What I Like About You, starring Amanda Bynes and Jennie Garth.
Zano made his first appearance in the second season and remained until the fourth and final season, which ended April 24, 2006. Afterwards, he went on to host and executive produce his Music Television reality show Why Can"t I Be You?.
The following year, Zano appeared alongside Haylie Duff and Frankie Muniz in the independent romantic comedy My Sexiest Year. The film, which received mixed reviews, had its world premiere at the 2007 Hamptons International Film Festival.
In 2008 he appeared in a supporting role opposite Drake Bell in Metro-Goldwyn-Mayer"s teen comedy film College.
Zano also appeared in Beverly Hills Chihuahua and Joy Ride 2: Dead Ahead later that year. In 2009, Zano co-starred in The Final Destination, the fourth installment of the Final Destination film series. He also guest starred on the American Broadcasting Company sitcom Cougar Town, starring Courteney Cox.
In 2010, he had a recurring role on The CW"s Melrose Place.
In 2011 he started a recurring role on 2 Broke Girls as Johnny, a graffiti artist who regularly flirts with Max (Dennings). In 2011 he also co-starred in the romantic comedy Scents and Sensibility as Brandon.
In 2012, Zano scored a recurring role on another CW show, 90210, in which he played a billionaire who goes into business with Annie (Shenae Grimes). Beginning in December 2012, Zano began a recurring role in season three of the American Broadcasting Company comedy series Happy Endings as Pete, Penny"s new love interest.
In February 2014, Zano signed on to play the male lead in Liz Feldman and Ellen DeGeneres" National Broadcasting Company comedy pilot One Big Happy.
The show was ordered to series on May 9, 2014, and will debut mid-season in early 2015. Zano was in a long-term relationship with fellow actor and singer Haylie Duff from December 2007 to November 2011. He also dated actress Kat Dennings from December 2011 to June 2014.