Career
He co-owns the company Trade Revolution (Pty) Limited., and is chairman of the non-profit organisation Missing Children Société Anonyme.
Panagio was born in Pretoria and attended Pretoria Boys High School. After graduating from the Method Actor"s Training Centre, he went on to play minor roles in Egoli and Generations. This preceded his taking up of a contract with 7de Laan, in which he played businessman George Kyriakis.
He joined Top Billing as a freelance presenter in 2007 after leaving 7de Laan and has since played in Zone 14, Ella Blue and Vallei van Sluiers.
He has presented the M-Net reality series Survivor South Africa since 2009. He has starred in various films, including Susanna van Biljon, Semi-Soet, Konfetti and Vrou Soek Boer.
Panagio was nominated for Best Actor at the 2012 SAFTAs for his role in Semi-Soet.