Background
Kolchanov, Nikolay Alexandrovich was born on January 9, 1947 in Omsk, Znamensky, Russia. Son of Alexander Leontievich and Anna Klimentievna (Bandkovskaya) Kolchanov.
(Molecular biology and genetics are fast-growing fields. G...)
Molecular biology and genetics are fast-growing fields. Genetic engineering and biotechnological innovations have also restructured our views of the field. Raw data from the wet lab are accumulated at an ever increasing rate since the beginning of the large-scale sequencing of genomes of model organisms and the human. The necessary involvement of scientists of widely-divergent backgrounds to analyze the data has been evident, and computers are intimately tied into the analysis of biological data. This volume is a collection of computer and mathematical treatments of current challenges of molecular biology and genetics. It is a product of the collaborative research work at the Computational Genetics and Biophysics Group (Supercomputer Computations Research Institute, USA), the Theoretical Molecular Genetics (Russian Academy of Sciences, Russia) and the Bioinformatics Group (Consiglio Nazionale delle Ricerche, Italy). Many of the chapters are firsthand results from these groups, interspersed by remarks to make each chapter self-consistent so that each can be read independently. The book emphazises the fundamental principles of the structural-functional organization of the three major classes of genetic macromolecules: DNA, RNA and proteins. It attempts to introduce universally applicable theoretical principles into the enormous realm of raw data. An integrative, theoretical computer approach is developed to analyze these macromolecules to gain insights into the complexities of their function and evolution. Topics include: analysis of structural-functional organization of nucleotide sequences, mobile genetic elements and transposable sequences, molecular mechanisms of mutagenesis, structural-functional organization of proteins and evolution of genetic macromolecules.
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Kolchanov, Nikolay Alexandrovich was born on January 9, 1947 in Omsk, Znamensky, Russia. Son of Alexander Leontievich and Anna Klimentievna (Bandkovskaya) Kolchanov.
Bachelor of Science, State University, Novosibirsk, Russia, 1971. Master of Science, State University, Novosibirsk, Russia, 1974. Doctor of Philosophy, Institute Cytology and Genetics, Novosibirsk, Russia, 1975.
Doctor of Science, Institute Cytology and Genetics, Novosibirsk, Russia, 1989. Professor (habilitation), Institute Cytology and Genetics, Novosibirsk, Russia, 1992.
Research assistant, Institute Cytology and Genetics, Novosibirsk, 1974-1983; senior scientist, Institute Cytology and Genetics, Novosibirsk, 1983-1989; department head, Institute Cytology and Genetics, Novosibirsk, since 1989. Associate director Institute Cytology and Genetics, Novosibirsk, since 1992.
(Molecular biology and genetics are fast-growing fields. G...)
Member Science Council Russian National Human Genome Project, Russian Academy of Sciences (science council molecular biology).
Married Valentina Mihailovna Bormotova, October 10, 1969. 1 child, Anna Nikolaevna.