He studied architecture in Germany and Switzerland and had several years of work in Oslo before he came to Trondheim.
He worked primarily in Trondheim, but he was also responsible for the design of buildings in other parts of Norway. He was a teacher of mechanics and architecture at Trondheim Technical Learning Institution, the precursor to the Norwegian Institute of Technology in 1871 and in 1891 he became the teacher of architecture and head of the architectural department. He is known for several works in different parts of the country.
Ole Falck Ebbell had a son Ole-Falk Ebbell (1879–1969), later: Ole-Falk Ebbell-Staehelin, who became civil engineer
He was a member of the commission for the restoration of the Nidaros Cathedral in Trondheim (1882-1894).