Background
The only son of Ludovico Orsini Migliorati (1425-1489) and Adriana del Mila (b 1434), Orsino was related to Alexander VI through his mother, who was the Pope"s cousin.
The only son of Ludovico Orsini Migliorati (1425-1489) and Adriana del Mila (b 1434), Orsino was related to Alexander VI through his mother, who was the Pope"s cousin.
Giulia was also the sister of the future Pope Paul III (née Alessandro Farnese). When the Cardinal expressed a desire to take her daughter-in-law for a mistress, Adriana immediately gave her permission and blessings to the affair. In exchange for his enforced compliance to his wife"s adultery with Rodrigo, Orsino was granted mayorship of the city of Carbognano.
Briefly concerned that a scandal would break out, Alexander VI did not acknowledge paternity, which was instead attributed to, and accepted by, Orsino.
These children include Girolama (b 1495), Isabella (b 1496) and Rodrigo, Duke of Nepi (b 1498). Orsino died in 1500, at age 27, of unknown causes.
At around the time of his death, Giulia and the Pope had become mildly estranged but his mother, Adriana, eventually brokered a peaceful separation of the two. Adriana died in about 1509, and the control of Carbognano passed to her erstwhile daughter-in-law, Giulia.
The vast Orsini family fortune was eventually inherited by Laura Orsini, the daughter of Giulia by Alexander VI.
