In 1971 he was appointed the first chair of the nine-member Philippine Medical Care Commission. This commission was tasked to provide medical insurance to poor Filipinos. The commission"s program ran for almost a quarter of a century.
He was chair for 12 years.
In the 1970s, Marcos headed a defense fund which supported two Filipina nurses accused of killing 10 patients in the Ann Arbor Hospital Murders. He called their conviction a "miscarriage of justice".
He owned, controlled, or had interests in 50 corporations, including a large car dealership, a sugar mill called Consolidate Sugar Corporation, a real estate firm called Citizens Development Incorporated, and Philippine Seed Incorporated. He did not join the Marcos family in Hawaii after the EDSA Revolution, and opted to stay in the Philippines in retirement.
In 1998 Marcos was the subject of a lawsuit over an under-collateralized "behest loan" in the amount of ₱60 million which his company, Bagumbayan Corporation, received from the Development Bank of the Philippines.
lieutenant was one of a series of lawsuits over behest loans given to associates of President The case was finally dismissed in 2007 by the Supreme Court, which said there was no evidence that the loan was given simply because Pacifico Marcos was a "crony" of the former president
Marcos did not involve himself in politics, and distanced himself from his brother"s regime when it grew unpopular during the 1980s. In a 1986 interview he said he was unaware of his brother"s wealth.
Marcos, a graduate of the University of the Philippines College of Medicine and a member of the Mu Sigma Phi Fraternity, was a President of the Philippine Medical Association.