Career
He was taken at pick number 25 in the 2010 national draft by the Brisbane Lions. Karnezis made his debut in round 13 of the 2011 season, against Richmond. On 25 October 2013 he was traded to the Collingwood Football Club in exchange for Jackson Paine.
He retired from American Federation of Labor-Congress at the conclusion of the 2015 season.
After his retirement from the highest level, Karnezis joined West Preston Lakeside of the Northern Football League (NFL).