Education
He received a Doctor of Philosophy degree in 1973 from Stanford University and an Bachelor of Surgery degree in 1968 from Massachusetts Institute of Technology.
He received a Doctor of Philosophy degree in 1973 from Stanford University and an Bachelor of Surgery degree in 1968 from Massachusetts Institute of Technology.
He is known for his research on deoxyribonucleic acid mismatch repair. Modrich was born on June 13, 1946, in Raton, New Mexico. Modrich joined Duke University"s faculty in 1976 and has been a Howard Hughes Investigator since 1995.
He works primarily on strand-directed mismatch repair.
His lab demonstrated how deoxyribonucleic acid mismatch repair serves as a copyeditor to prevent errors from deoxyribonucleic acid polymerase. Matthew Meselson previously proposed the existence of recognition of mismatches.
Modrich performed biochemical experiments to study mismatch repair in East. coli. They later searched for proteins associated with mismatch repair in humans.
National Academy of Sciences. American Academy of Arts and Sciences.