I Pei-chi graduated from the Hubei College of Languages and became a member of the faculty of the Higher Normal School and the Technical institute of Hunan in 1913.
Mr. I was appointed president of the First Normal School of Hunan in 1919 and acted concurrently as chairman of the Provincial Commission of Education. In 1920 he became a chief secretary to the Civil Governor of Hunan and at the same time acted as president of the Provincial Library of Hunan.
I Pei-chi resumed his officre as a professor at Guangdong University in 1922. He held a chair at the National University, Peking in 1923 and the same year was appointed Minister of Education. I Pei-chi was made a president of the Teachers' College for Girls and a member of the Sino-French Committee on Boxer Indemnity in 1924.
In 1927 Mr. I was appointed president of the National Labor University and a member of the Bureau of Agriculture of the Central Party Headquarters. When the Ministry of Agriculture and Mining was created in 1928 he became Minister and at the same time was a member of the Political Council of the Central Executive Committee, a member of the Diplomatic Committee, a member of the Reconstruction Committee and a member of the University Council of the National Government.
After the abolition of the Ministry of Agriculture and Mining at the 4th Plenary Session of the Central Executive Committee, Mr. I was appointed president of Peking High Normal University, Peking. He became a director of the Palace Museum in Peking in 1931, but was forced to resign in 1932 on the charge of misappropriation of the palace treasures.
He was impeached by the Control Yuan and proscribed by the National Government on the charge. I Pei-chi was reported to be living in retirement in Dalian.