Princess Louisa was born on 19 March 1749, at Leicester House, Westminster, London, and was christened there on 11 April. Her father was Frederick, Prince of Wales, eldest son of George II and Caroline of Ansbach. Her mother was The Princess of Wales (née Augusta of Saxe-Gotha).
Her health was delicate throughout her life. In 1764, negotiations were made between the British and Danish royal houses of a marriage between the Danish heir to the throne and a British princess. The preferred choice for a bride was initially princess Louisa, but after the Danish representative in London, Count von Bothmer, was informed of her weak constitution, her two years younger sister Caroline Mathilda was chosen for the match instead.
The marriage was announced in Great Britain 10 January 1765.
Princess Louisa died, at Carlton House, London, on 13 May 1768, unmarried, and without issue, at the age of 19. Titles and styles
19 March 1749 – 13 May 1768: Her Royal Highness Princess Louisa.
