Career
He was also a Yiddish linguist, philologist, lawyer and scholar of considerable renown. Pryłucki was a respected attorney and was said to have had "leadership over the scattered (non-Zionist) national clubs, societies, and groups". In 1910–1936, Pryłucki was the editor of the Folkist newspaper Warszawer Togblat (The Warsaw Daily), later renamed as Der Moment.
In 1922–1927 he was reelected to the Sejm on the Bloc of National Minorities list.
Pryłucki authored numerous books on Yiddish folklore, philology, culture and theatre, published in Warsaw. He once said of Yiddish theatre that it did not arise simultaneously with theatre in other European "national" languages.
He conjectured that this was at least in part because the Jewish sense of nationality favored Hebrew over Yiddish as a "national" language, but few Jews of the period were actually comfortable using Hebrew outside of a religious/liturgical context. After Soviet forces took Vilna in January 1941, he was appointed the head of the YIVO Institute.
He was eventually murdered by the Gestapo in Vilnius (Vilno) in August 1941.