Career
He is known above all for his portrait busts and imaginary portraits. At the Salon of 1789, he showed a portrait head of Belisarius. Deseine trained in several ateliers, notably with Augustin Pajou, whose portrait bust he exhibited at the Salon of 1785.
In 1814 he published a history of the Académie royale de peinture et de sculpture, of which he had been a member.
By Deseine are at the musée du Louvre ("Étude d"un homme debout avec une draperie sur l"épaule") and the musée Condé, Chantilly ("Le Déluge", "Deux Romains saluant un empereur assis" and "Lars Porsenna"). The musée Condé also conserves two projects for the monument to the duc d"Enghien.