He was the great grandson of the founder of the John Enschedé company, and the oldest son of Johannes Enschedé Junior. Like his father and grandfather before him, he was a member of the Dutch Society of Science and the Teylers Second Society.
He studied law in Leiden and returned to become partner in the family company at the young age of 20, where he became editor of the Opregte Haarlemsche Courant.
From this marriage was born on november 20, 1811 a son: Johannes Enschedé IV. Like his father, he was a regent of the Saint Elizabeth"s-Gasthuis and the Hofje van Staats en Noblet.
Johannes Enschedé III was judge of instruction, Auditor soldier, a member of the Municipal Council and member of the House of Representatives (Netherlands).
