Background
Maria Anna was born at the Royal Palace in Naples. Her father was Ferdinand, Duke of Calabria, the third son and ninth child of Charles III of Spain and Maria Amalia of Saxony. Her mother was the Archduchess of Austria, the tenth daughter and thirteenth child of the famous Maria Theresa of Austria and her husband, Francis I, Holy Roman Emperor.
Career
She was styled Princess of Naples and Sicily. She was baptised during the first year of her life. Her full name was Maria Anna Giuseppa Antoinette Francesca Gaetana Teresa Amalia Clementina, a namesake of her father"s sister who died in infancy.
She was born and died while her father was still styled Duke of Calabria.
She was then styled Princess of Naples and Sicily. He also died in childhood, yet Maria Anna outlived him.
Carlo eventually succumbed to the illness on 17 December 1778, aged just three. In 1778, against all efforts, she contracted smallpox.
She rallied for a while, but died on 22 February 1780.
Titles and styles
23 November 1775 – 22 February 1780 Her Royal Highness Princess Maria Anna of Bourbon-Two Sicilies (Principessa Maria Anna di Borbone delle Due Sicilie).