Education
She studied at Harvard University and obtained her doctorate at Freiburg in 1898.
She studied at Harvard University and obtained her doctorate at Freiburg in 1898.
She investigated embryogenesis, in particular the head development, from studying sharks and salamanders. Her most notable contribution to the field was her demonstration that neural crest cells formed the jaw cartilage and tooth dentine in salamanders, but her work was not believed by her contemporaries. Her claim went counter to the belief that only mesoderm could form bones and cartilage.
Her hypothesis of the neural crest origin of the cranial skeleton gained acceptance only some 50 years later when confirmed by Sven Hörstadius and Sven Sellman.
Unable to secure a university position, she said "if I cannot obtain the work I wish, then I must take up with the next best" and then became active in politics, including tearing down a fence to give the public access to the beach. In 1931, at the age of 74, she became mayor of Pacific Grove, California.
According to Palumbi and Sotka, her prescient pioneering setting up of a marine protected area was crucial to the recovery of the sea otter.
Quotations: "if I cannot obtain the work I wish, then I must take up with the next best".